Dual Individual Distributed Genetic Algorithm for Minimizing Energy of Protein Tertiary Structure

نویسندگان

  • Tomoyuki Hiroyasu
  • Mitsunori Miki
  • Takashi Iwahashi
  • Yuko Okamoto
  • Jack Dongarra
چکیده

This paper describes Genetic Algorithm (GA) for finding the protein tertiary structure that has the minimum energy. In the conventional study, Simulated Annealing (SA) is used to be applied for this problem. In the previous studies, it is also reported that it is difficult to find the optimum solutions by GAs. Dual individual Distributed Genetic Algorithm (Dual DGA) is one of DGAs and is good at global search. The Dual DGA also maintains the diversity of the solutions. Therefore, it can be supposed that they can get a good solution in finding the protein tertiary structure. The target protein in this paper is Met-enkephalin that is consisted of 5 amino acids sequences. The results showed that the Dual DGA can find the solution successfully and Dual DGA has the higher searching capability than SA.

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Dual Individual Distributed Genetic Algorithm for Minimizing the Energy of Protein Tertiary Structure

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تاریخ انتشار 2003